Current volume of antimicrobial use in Japan (unit: tons)[Current status of antimicrobial use in Japan]

Antimicrobial selection pressure in Japan from a One Health perspective is highest among tetracyclines at 19-21%, followed by penicillins at 13-15%, and macrolides at 11-13%. Use of both penicillins and macrolides has been growing over recent years, so caution regarding future trends will be required. On the other hand, the fact that barely any changes in cephalosporins and fluoroquinolones were observed is attributed to differences in the antimicrobials that can be used in humans and in non-humans.