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A statistical information site that deepens the understanding of AMR (drug resistance) and one health

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The Research Institute of Tuberculosis, Japan Anti-tuberculosis Association

http://www.jata.or.jp/english/

Among patients with culture-positive pulmonary tuberculosis who were newly notified from 2011 to 2017, the proportion of resistance to major antituberculosis antibiotics—isoniazid (INH), rifampicin (RFP), streptomycin (SM), and ethambutol (EB)—remained mostly at the same level, but there was a rise of up to 1.1 percentage points in streptomycin (SM) resistance in 2017 compared with the levels between 2012 and 2016. The number of newly reported cases with multidrug-resistant tuberculosis that are resistant at least to both INH and RFP remained in the range of 50 to 60 (0.5-0.7%) per year.

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* The denominator was defined as the number of patients with recorded INH- and RFP-susceptibility testing results among all culturepositive patients: 8,046 (73.7%) patients in 2011, 8,347 (74.1%) patients in 2012, 7,701 (73.2%) patients in 2013, 7,645 (74.5%) patients in 2014, 7,630 (76.0%) patients in 2015, 7,732 (78.3%) patients in 2016, and 7,891 (82.4%) patients in 2017.
-: Not under surveillance.
† INH- and RFP- resistant tuberculosis bacteria are referred to as "multidrug-resistant."
§ The proportion appeared here showed the share in patients with INH- and RFP-susceptibility testing results, excluding those who were not tested for SM-susceptibility or those with the unknown test result: 54 patients in 2012, 48 patients in 2013, 52 patients in 2014, 48 patients in 2015, 47 patients in 2016 and 51 patients in 2017.
¶ The proportion appeared here showed the share in patients with INH- and RFP-susceptibility testing results, excluding those who were not tested for EB-susceptibility or those with the unknown test result: 14 in 2012, 13 in 2013, 13 in 2014, 19 in 2015, 17 in 2016 and 14 in 2017).
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"Source: Nippon AMR One Health Report (NAOR) 2018"