National Institute of Infectious Diseases
The 32, 46, and 31 Salmonella Typhi strains that were respectively isolated in 2015, 2016, and 2017 were tested for antimicrobial susceptibility. Ciprofloxacin (CPFX)-non-susceptible strains respectively accounted for 68.8%, 63.0%, and 83.9%. Strains with advanced resistance (MIC ≥ 4) to ciprofloxacin accounted for 12.5%, 23.9%, and 16.1%, respectively. Multidrug-resistant Salmonella Typhi that indicated resistance to ampicillin (ABPC), chloramphenicol (CP) and ST were isolated in all years (two strains in 2015, one strain in 2016, and four strains in 2017), including six strains (one each in 2015 and 2016, and four in 2017) that were non-susceptible to ciprofloxacin (CPFX).